While 〜 To take advantage of a moment of time to do something (there is an element of cunning in its meaning) (1)kare ga yudan shiteiru suki ni kishuu shite hoshin da zo. The best thing to do is to attack him when his guard is down. 時間に少し開いている隙間を最高の機会とし、そのチャンスを逃さないうちにずるかしこい行為をする。